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This product contains Proteoglycan derived from salmon cartilage and Collagen Type II derived from salmon cartilage. These two ingredients are reported to improve the function, and bending and stretching movement of the knee joint in middle-aged and elderly healthy people.
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※Articular cartilage components without water
References:Ann.rheum.Dis.1973 Jul;32(4):364-378

Proteoglycan contains proteins and chondroitin sulfate and is widely found into the body such as in cartilage and skin.
Excellent in water retention and elasticity, it has the function of absorbing impact.

A type of protein mainly found in cartilage such as in joints and in the eyeball.
It has the function of preserving the cartilage structure.

Clinical studies have confirmed that the ingestion of "salmon cartilage-derived proteoglycan" and "salmon cartilage-derived type II collagen" improves the movement of the knee joint that involves bending and stretching.

The subjects of the clinical study were 60 healthy males and females aged between 40 and 70 who were asked to take a tablet containing Proteoglycan complex 80 (16 mg of Proteoglycan and 16 mg of type II collagen derived from salmon) or a placebo over a period of 12 weeks. The study was concerning “discomfort when sitting in the traditional Japanese seiza position” (stiffness, discomfort and pain in the knees when kneeling and sitting on your heels (seiza)), and the results confirmed a significant difference between the two groups.
<Source: Japanese Pharmacology & Therapeutics Vol.45 No.2 2017>
※This is an example presented from the research papers on the subject, it is not a clinical study carried out using this product.
Take 1 tablet per day with water without chewing.

※Please observe the daily intake recommendation and refrain from excessive consumption.
※This product is no food coloring used. It may vary in color of capsule due to natural ingredients but it does not affect the quality of the product.
Reduced maltose starch syrup (Produced in Japan), Salmon cartilage extract, Agar / Crystalline cellulose, Shellac, Calcium stearate, Fine silicon dioxide, Carnauba wax

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